What the trials used
Nothing in the clinical record resembles how the stack is used. Ipamorelin’s patient trial gave 0.03 mg/kg intravenously twice a day, in hospital, to people recovering from bowel surgery: about 2.4 mg per dose for an 80 kg adult, roughly ten times a community dose, through a drip. CJC-1295’s volunteer trials gave 30 to 90 mcg/kg of the DAC form, 2.4 to 7.2 mg for the same adult, as a single or weekly injection. The no-DAC form has no trial dose because it has no trial.
What the community runs
The pattern that repeats across clinic protocols, vendor pages, and forum threads:
100 to 300 mcg of CJC-1295 (no DAC) and 100 to 300 mcg of ipamorelin per injection, almost always in a 1:1 ratio, often from a pre-mixed blend vial.
One to three injections a day. Before bed is the constant. Post-workout and on waking are common additions.
On an empty stomach, at least two hours after eating, because insulin and fatty acids blunt the growth-hormone response.
Eight to twelve weeks, then a break, although a large share of users run it continuously.
Users of the DAC form instead inject 1 to 2 mg once or twice a week.
The 1:1 ratio, the 200 to 300 mcg figure, and the bedtime timing all trace back to forum convention, not to any dose-finding study. Nobody has tested whether 100 mcg would do the same, or whether three times a day does more than once.
Reconstitution arithmetic
Research-labelled product comes as lyophilised powder, as separate 5 mg vials or as a 5 mg/5 mg blend (10 mg total), and you add bacteriostatic water yourself. Concentration is milligrams divided by millilitres, the dose in millilitres is the dose you want divided by that concentration, and on a U-100 insulin syringe 1 mL is 100 units.
Vial BAC water Concentration 100 mcg 200 mcg 300 mcg
5 mg single peptide 2 mL 2.5 mg/mL 0.04 mL (4 units) 0.08 mL (8 units) 0.12 mL (12 units)
5 mg single peptide 2.5 mL 2 mg/mL 0.05 mL (5 units) 0.1 mL (10 units) 0.15 mL (15 units)
5 mg / 5 mg blend (10 mg total) 2 mL 5 mg/mL total, 2.5 mg/mL each 0.04 mL (4 units) = 100 mcg each 0.08 mL (8 units) = 200 mcg each 0.12 mL (12 units) = 300 mcg each
5 mg / 5 mg blend (10 mg total) 3 mL 3.33 mg/mL total, 1.67 mg/mL each 0.06 mL (6 units) = 100 mcg each 0.12 mL (12 units) = 200 mcg each 0.18 mL (18 units) = 300 mcg each
With 2 mL of water, a 200 mcg dose is 8 units on the syringe, and a one-unit misread is a 12% error; more water makes the volume easier to measure. A blend vial also fixes the ratio, so a different split means separate vials. Run your own numbers through the reconstitution calculator and the dosage calculator rather than copying a row.
No validated protocol
There is no validated protocol for this stack. The only trial doses that exist were a hospital drip for a bowel condition and a weekly shot of a different molecule.
Conclusion
There is a clear gap between trial dosing and community dosing. Adjusting doses without a validated protocol significantly amplifies risk.